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Have you ever wondered how to find out if someone has a methylation problem? Well you have probably heard to doing saliva or blood tests to see which genes a person was born with.  And that is certainly one way to figure out if someone has a methylation problem.  Tests like that are valuable but they can be time consuming and a bit expensive as well.  So I’d like to share with you a better and faster way to figure out if someone you  know has a methylation problem.

First, allow me to quote one of my favorite pieces of research:

“Folate metabolism can influence the final form of any growing tissue due not only to its participation in nucleic acid synthesis, but also to its known function in regulating DNA and protein methylation.”  – Bio Med Central Medical Genetics. 2011 May 26;12:75.

Folate, ie mother nature’s #1 methyl donor, can impact the final form of any growing tissue in the body!  That is proof positive that the methylation cycle can not only afffect how you FEEL but it can also affect how you LOOK.  In fact, as the video below explains, there are all kinds of physical signs that point to methylation problems.


Each of the following health conditions and physical characteristics suggests a methylation problem is at play:

  • Epicanthal folds, hypertelorism, low set ears
  • Neural tube defects of all kinds,  incl. spina bifida
  • Down’s Syndrome
  • Fetal Alcohol Syndrome
  • Klienfelter’s Syndrome
  • Marfan’s Syndrome
  • All other trisomies and anueploidies
  • Cleft palate
  • Austism spectrum
  • Arnold-Chiari Malformation
  • Short limbs
  • Scoliosis
  • Any midline defect present at birth
  • Essentially all congenital abnormalities

Do you know anyone in your life who has some of the issues discussed in that video or listed in this article?  If so, they need to work on balancing their methylation cycle and should be working with a professional who is knowledgeable about this type of health concern.  You may find a practitioner in your area from

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  • July 30, 2014 Reply

    Chanon Starnes

    HI Dr. Rostenberg, I recently found out I may have the MTHFR gene defect. I am currently in the process of getting the genetic test results. My question is for my 15 year old daughter.. We discovered her scoliosis at age 13..she has two curves the thoracic being the more severe one. She also has the long fingers and is a very thin frame. I am planning to get the genetic test for her. Based on your research, it is too late for her scoliosis if we do find she has the defect too? Have you come across any cases where the scoliosis improved with supplementation and diet?

    Thank you so much for your work!
    Chanon Starnes

    • July 31, 2014 Reply


      Hi Chanon,

      I recommend the Clear Institute for all questions related to scoliosis. The Clear Institute is the leader in treating scoliosis once it has been discovered. She likely has a genetic component to her scoliosis and I can help you support her nutritionally to prevent other issues from showing up. The description of the long fingers, etc., are consistent with the “methylation” phenotype. Regardless of which genes she has, she can find an optimum balance and get better. For treating the scoliosis once it is already present in the spine, you need to reach out to the experts in the chiropractic field, the Clear Institute. For the genetic support and methylation support, I can help you with that directly. If you have any questions please contact my office and 208-322-7755. Thank You. Dr. Rostenberg

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