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Regardless of our genes if we want to improve the health of the brain, we must improve the health of the gut.  Without question the gut must be functioning properly BEFORE the rest of the body can be treated.  Since the COMT system breaks down stress hormones, it is important to calm down the body’s immune system.  The immune system uses chemical messengers, called cytokines, to communicate within the body.  The problem arises when the immune system gets irritated and alarmed and begins to send stressful, alarming cytokines into the blood stream.

So the goal with supplements and diet is to limit the release of stress hormones.  And we do that by calming down the immune system and healing the gut through eating low-inflammatory foods and taking supplements which help reduce inflammation and catecholamines even more.  Below you will find my favorite supplements for calming down the immune system in the brain, balancing hormones, and removing chemical poisons.  You will also find a general diet guideline that promotes long-term brain health as well.


Recommended Eating Habits for Optimum COMT and MAO Function:                                  

There are many popular diets today – paleo, GAPS, SCD, vegetarian, vegan, etc. I personally prefer a modified paleo diet – organic meat, vegetables, nuts/seeds, healthy fats, and small amounts of rice or gluten-free grains.  The brain tends to thrive on diets that focus on fats and protein while minimizing refined carbohydrates.  But everyone is different and there is no single diet that works for everyone!  Regardless of which diet you are on, the following rules apply:

  1. Eat frequently throughout the day.
  2. Avoid excess fruits, sugars, and carbohydrates that spike blood sugar leading to crashes.
  3. Make sure to eat protein and healthy fats like coconut oil, olive oil and avocado with every meal.

If you want a good “paleo-style” diet to follow, I recommend you use this Modified Elimination Diet as your guide.  I have made notes in red that I always share with patients in my office. You may view and print my notes and diet recommendations below:



Recommended Supplements for Optimum COMT and MAO Function:                                  

Dynamic Inflam-Eze   – Formulated to reduce inflammation, heal the gut, and calm down the immune system.†

Nutri-ChelX – Upregulates the removal of heavy metals (high iron, mercury, etc.) in a safe fashion by increasing metallothionein production in the cells.  This product also will upregulate glutathione levels to further support detox.†

Stress Essentials Relax – Improves bile flow with Taurine, increases glutathione, and promotes a sense of calm by increasing the GABA/Glutamate ratio in the brain.†

Crave-Curb – Designed to support a positive mood and a restful, relaxed state through beneficially modulating the metabolism of serotonin. This formula features clinically effective levels of 5-HTP and theanine per daily serving.†

OmegaPure DHA 600 – Targeted support for brain health, cognitive function & eye health.†


All supplements in this nutritional protocol can be purchased online through Dr. Rostenberg’s online pharmacy. Getting the supplements shipped to your door is very easy. Just follow the instructions below:

These supplements are available from our Nutri-Dyn web store and our prices are competitive with other outlets.

Just click on “Create an Account” in the top right corner to get started. The practitioner code is 703900.

Nutri-Dyn batch tests every single raw ingredient.  Meaning, they test every batch, every time before it is processed into a supplement.  I’m not aware of any other company that puts that kind of expense and effort into product quality.

Yours in Health,

Dr. Rostenberg


†This statement has not been evaluated by the FDA.  This product is not intended to diagnose, treat, cure, or prevent any disease.

†The information provided on this site is intended for your general knowledge only and is not a substitute for professional medical advice or treatment for specific medical conditions. You should not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

†In the event of a medical emergency, call a doctor or 911 immediately. Reliance on any information provided by this website is solely at your own risk.